Rabbit polyclonal anti-HMGCR antibody (STJ24046) is suitable for use in Western Blot and Immunohistochemistry.
2020-01-08
Antibody properties References Host Reactivity Antibody type Conjugate 2015-08-01 Monoclonal Anti-HMGCR antibody produced in mouse Prestige Antibodies ® Powered by Atlas Antibodies, clone CL0260, purified immunoglobulin, buffered aqueous glycerol solution : human: immunohistochemistry, western blot pricing 2016-10-01 Rabbit Polyclonal HMGCR antibody. Validated in WB, ICC/IF, IHC-P. Tested in Human, Mouse, Rat. Cited in 1 reference(s). Anti-HMGCR Antibody. 3-hydroxy-3-methylglutaryl-CoA reductase References (1) Recommended Applications Genetic validation in WB by siRNA knockdown. Product Description Monoclonal Antibody against Human HMGCR Open Datasheet.
Anti-HMGCR antibody produced in rabbit Prestige Antibodies ® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution Synonym: Anti-3-Hydroxy-3-methylglutaryl-CoA reductase Human Protein Atlas Number HPA008338 Human Protein Atlas - View RNA & protein expression data of this target 2016-10-01 · Anti-HMGCR antibodies showed good discrimination between (a) immune-mediated necrotizing myopathies (IMNM) and all controls (except idiopathic inflammatory myopathies (IIM)), (b) IMNM and all controls, (c) IMNM vs. IIM. (d) Moderate discrimination was also found for all IIM (including IMNM) vs. all controls. Select HMGCR antibodies from monoclonal antibodies listed below.
HMGCR antibody–associated myopathies can be considered in the context of the common clinical classification and our proposed pathologic groups of immune myopathies. 3 Polymyositis and inclusion body myositis can be ruled out because there are few lymphocytic inflammatory foci or inclusion bodies in HMGCR myopathies. HMG-CoA reductase is the rate-limiting enzyme for cholesterol synthesis and is regulated via a negative feedback mechanism mediated by sterols and non-sterol metabolites derived from mevalonate, the product of the reaction catalyzed by reductase.
HMGCR Antibody detects endogenous levels of total HMGCR. RRID: AB_2838480 Please cite this product as: Affinity Biosciences Cat# DF6518, RRID:AB_2838480. Format: Liquid. Concentration: 1mg/ml. Storage Condition and Buffer:
Anti-HMGCR myopathy was first recognized and characterized in patients with a history of statin exposure and immune-mediated necrotizing myopathy. After the discovery of anti-HMGCR autoantibodies, several international groups identified and characterized more patients, expanding the phenotypic spect … Recently, auto-antibodies (AAbs) to the enzyme, 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) was shown to be a MSA that was strongly associated with immune mediated necrotising myopathy (Arthritis Rheum.
LIA f, u f, u SRP-antikroppar HMGCR-antikroppar SRPAb HMGCRAb Kä Anti-phospholipid antibodies may indicate phospholipid antibody syndrome.
Validated for ELISA, IHC and WB. HMGCR (3-Hydroxy-3-Methylglutaryl-CoA Reductase) is a Protein Coding gene. Diseases associated with HMGCR include Familial Hyperlipidemia and Sitosterolemia.Among its related pathways are Sterol Regulatory Element-Binding Proteins (SREBP) signalling and … HMGCR antibodies; LDLCQ3 antibodies; Custom Antibodies. If you can't find the antibody you're looking for, why not consider a custom reagent from one of these suppliers. View custom suppliers. Calculators.
Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered
Anti-HMGCR antibody produced in rabbit (Anti-3-hydroxy-3-methylglutaryl-CoA reductase, LDLCQ3); ~ 1.0mg/mL, affinity isolated antibody; Suitable for western
Anti-HMGCR Polyclonal, Catalog # 13533-1-AP. Tested in Western Blot (WB) and Immunohistochemistry (Paraffin) (IHC (P)) applications. This antibody reacts
Rabbit Polyclonal Anti-HMG-CoA Reductase/HMGCR Antibody. Validated: ICC/IF , IHC, IHC-P. Tested Reactivity: Human, Mouse, Rat. 100% Guaranteed. HMGCR Antibody (C-1) is a high quality monoclonal HMGCR antibody suitable for the detection of the HMGCR protein of mouse, rat and human origin.
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Western blot analysis of extracts of various cell lines, using HMGCR antibody (STJ115278) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.
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Anti-HMGCR antibodies in necrotizing myopathies.
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Immunofluorescence analysis of A549 cell using HMGCR antibody. Blue: DAPI for nuclear staining. Rabbit anti-HMGCR Antibody.
Among its related pathways are Sterol Regulatory Element-Binding Proteins (SREBP) signalling and Regulation of cholesterol biosynthesis by SREBP (SREBF).
Polyclonal Antibody to 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase (HMGCR). Polyclonal antibody preparation. Size: 100 ug. Reactivity: Rattus
PMID: 24708688; HMGCR is upregulated in hepatocellular carcinoma associated with paraneoplastic hypercholesterolemia. PMID: 23549978 Antibody information for antibodies HPA008338 and CAB016797 used in analysis of ENSG00000113161 / HMGCR We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies.
As a single case report, the presented clinical and laboratory findings can only be considered hypothesis generating. It is unclear whether anti‐HMGCR IgG antibodies to 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) are mainly associated with necrotizing autoimmune myopathy (NAM) in a subset of statin-treated patients. Although infrequent, these antibodies may also be observed in statin-naive patients with NAM. 2020-08-13 HMGCR : Evaluating patients with suspected necrotizing autoimmune myopathy Measuring 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) antibodies 2020-01-08 HMGCR antibody Rabbit Polyclonal from Proteintech validated in Immunohistochemistry (IHC), Immunofluorescence (IF),Enzyme-linked Immunosorbent Assay (ELISA) applications. This antibody reacts with human, mouse, rat samples. Cat.No. 13533-1-AP. Antibody information for antibodies HPA008338 and CAB016797 used in analysis of ENSG00000113161 / HMGCR () We use cookies to enhance the usability of our website.